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phenobarbital will lessen the extent or outcome of disopyramide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Not known.phenobarbital will decrease the level or outcome of saxagliptin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unfamiliar.If this SPL is made up of inactivated